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HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

INTRODUCTION: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas from patients treated within the neoadjuvant...

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Detalles Bibliográficos
Autores principales:	Denkert, Carsten, Huober, Jens, Loibl, Sibylle, Prinzler, Judith, Kronenwett, Ralf, Darb-Esfahani, Silvia, Brase, Jan C, Solbach, Christine, Mehta, Keyur, Fasching, Peter A, Sinn, Bruno V, Engels, Knut, Reinisch, Mattea, Hansmann, Martin-Leo, Tesch, Hans, von Minckwitz, Gunter, Untch, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672694/ https://www.ncbi.nlm.nih.gov/pubmed/23391338 http://dx.doi.org/10.1186/bcr3384

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