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A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer
INTRODUCTION: Fulvestrant shows dose-dependent biological activity. Greater estrogen-receptor (ER) blockade may feasibly be achieved by combining fulvestrant with anastrozole. This pre-surgical study compared fulvestrant plus anastrozole versus either agent alone in patients with ER-positive breast...
Autores principales: | Robertson, John FR, Dixon, J Michael, Sibbering, D Mark, Jahan, Ali, Ellis, Ian O, Channon, Eddie, Hyman-Taylor, Pauline, Nicholson, Robert I, Gee, Julia MW |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672778/ https://www.ncbi.nlm.nih.gov/pubmed/23497452 http://dx.doi.org/10.1186/bcr3393 |
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