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Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling
INTRODUCTION: Although oestrogen is essential for the development of the normal breast, adult mammary stem cells are known to be oestrogen receptor alpha (ER) negative and rely on paracrine signals in the mammary epithelium for mediation of developmental cues. However, little is known about how syst...
Autores principales: | Harrison, Hannah, Simões, Bruno M, Rogerson, Lynsey, Howell, Sacha J, Landberg, Göran, Clarke, Robert B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672803/ https://www.ncbi.nlm.nih.gov/pubmed/23497505 http://dx.doi.org/10.1186/bcr3396 |
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