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Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening
INTRODUCTION: For early detection of breast cancer, the development of robust blood-based biomarkers that accurately reflect the host tumor is mandatory. We investigated DNA methylation in circulating free DNA (cfDNA) from blood of breast cancer patients and matched controls to establish a biomarker...
Autores principales: | Kloten, Vera, Becker, Birte, Winner, Kirsten, Schrauder, Michael G, Fasching, Peter A, Anzeneder, Tobias, Veeck, Jürgen, Hartmann, Arndt, Knüchel, Ruth, Dahl, Edgar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672828/ https://www.ncbi.nlm.nih.gov/pubmed/23320751 http://dx.doi.org/10.1186/bcr3375 |
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