Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor

In this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized condit...

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Detalles Bibliográficos
Autores principales: Kuang, Hua, Xing, Changrui, Hao, Changlong, Liu, Liqiang, Wang, Libing, Xu, Chuanlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673080/
https://www.ncbi.nlm.nih.gov/pubmed/23539028
http://dx.doi.org/10.3390/s130404214
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author Kuang, Hua
Xing, Changrui
Hao, Changlong
Liu, Liqiang
Wang, Libing
Xu, Chuanlai
author_facet Kuang, Hua
Xing, Changrui
Hao, Changlong
Liu, Liqiang
Wang, Libing
Xu, Chuanlai
author_sort Kuang, Hua
collection PubMed
description In this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized conditions. The visual limit of detection (LOD) of the amplified method for qualitative detection lead ions was 2 ng/mL and the LOD for semi-quantitative detection could go down to 0.19 ng/mL using a scanning reader. The method suffered from no interference from other metal ions and could be used to detect trace lead ions in drinking water without sample enrichment. The recovery of the test samples ranged from 96% to 103%. As the detection method could be accomplished within 15 min, this method could be used as a potential tool for preliminary monitoring of lead contamination in drinking water.
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spelling pubmed-36730802013-06-19 Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor Kuang, Hua Xing, Changrui Hao, Changlong Liu, Liqiang Wang, Libing Xu, Chuanlai Sensors (Basel) Article In this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized conditions. The visual limit of detection (LOD) of the amplified method for qualitative detection lead ions was 2 ng/mL and the LOD for semi-quantitative detection could go down to 0.19 ng/mL using a scanning reader. The method suffered from no interference from other metal ions and could be used to detect trace lead ions in drinking water without sample enrichment. The recovery of the test samples ranged from 96% to 103%. As the detection method could be accomplished within 15 min, this method could be used as a potential tool for preliminary monitoring of lead contamination in drinking water. Molecular Diversity Preservation International (MDPI) 2013-03-28 /pmc/articles/PMC3673080/ /pubmed/23539028 http://dx.doi.org/10.3390/s130404214 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license(http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Kuang, Hua
Xing, Changrui
Hao, Changlong
Liu, Liqiang
Wang, Libing
Xu, Chuanlai
Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title_full Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title_fullStr Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title_full_unstemmed Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title_short Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
title_sort rapid and highly sensitive detection of lead ions in drinking water based on a strip immunosensor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673080/
https://www.ncbi.nlm.nih.gov/pubmed/23539028
http://dx.doi.org/10.3390/s130404214
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