Cargando…
Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers
The paper presents the potential of an electronic nose technique in the field of fast diagnostics of patients suspected of Chronic Obstructive Pulmonary Disease (COPD). The investigations were performed using a simple electronic nose prototype equipped with a set of six semiconductor sensors manufac...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673123/ https://www.ncbi.nlm.nih.gov/pubmed/23591962 http://dx.doi.org/10.3390/s130405008 |
_version_ | 1782272214505095168 |
---|---|
author | Dymerski, Tomasz Gębicki, Jacek Wiśniewska, Paulina Śliwińska, Magdalena Wardencki, Waldemar Namieśnik, Jacek |
author_facet | Dymerski, Tomasz Gębicki, Jacek Wiśniewska, Paulina Śliwińska, Magdalena Wardencki, Waldemar Namieśnik, Jacek |
author_sort | Dymerski, Tomasz |
collection | PubMed |
description | The paper presents the potential of an electronic nose technique in the field of fast diagnostics of patients suspected of Chronic Obstructive Pulmonary Disease (COPD). The investigations were performed using a simple electronic nose prototype equipped with a set of six semiconductor sensors manufactured by FIGARO Co. They were aimed at verification of a possibility of differentiation between model reference mixtures with potential COPD markers (N,N-dimethylformamide and N,N-dimethylacetamide). These mixtures contained volatile organic compounds (VOCs) such as acetone, isoprene, carbon disulphide, propan-2-ol, formamide, benzene, toluene, acetonitrile, acetic acid, dimethyl ether, dimethyl sulphide, acrolein, furan, propanol and pyridine, recognized as the components of exhaled air. The model reference mixtures were prepared at three concentration levels—10 ppb, 25 ppb, 50 ppb v/v—of each component, except for the COPD markers. Concentration of the COPD markers in the mixtures was from 0 ppb to 100 ppb v/v. Interpretation of the obtained data employed principal component analysis (PCA). The investigations revealed the usefulness of the electronic device only in the case when the concentration of the COPD markers was twice as high as the concentration of the remaining components of the mixture and for a limited number of basic mixture components. |
format | Online Article Text |
id | pubmed-3673123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-36731232013-06-19 Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers Dymerski, Tomasz Gębicki, Jacek Wiśniewska, Paulina Śliwińska, Magdalena Wardencki, Waldemar Namieśnik, Jacek Sensors (Basel) Article The paper presents the potential of an electronic nose technique in the field of fast diagnostics of patients suspected of Chronic Obstructive Pulmonary Disease (COPD). The investigations were performed using a simple electronic nose prototype equipped with a set of six semiconductor sensors manufactured by FIGARO Co. They were aimed at verification of a possibility of differentiation between model reference mixtures with potential COPD markers (N,N-dimethylformamide and N,N-dimethylacetamide). These mixtures contained volatile organic compounds (VOCs) such as acetone, isoprene, carbon disulphide, propan-2-ol, formamide, benzene, toluene, acetonitrile, acetic acid, dimethyl ether, dimethyl sulphide, acrolein, furan, propanol and pyridine, recognized as the components of exhaled air. The model reference mixtures were prepared at three concentration levels—10 ppb, 25 ppb, 50 ppb v/v—of each component, except for the COPD markers. Concentration of the COPD markers in the mixtures was from 0 ppb to 100 ppb v/v. Interpretation of the obtained data employed principal component analysis (PCA). The investigations revealed the usefulness of the electronic device only in the case when the concentration of the COPD markers was twice as high as the concentration of the remaining components of the mixture and for a limited number of basic mixture components. Molecular Diversity Preservation International (MDPI) 2013-04-15 /pmc/articles/PMC3673123/ /pubmed/23591962 http://dx.doi.org/10.3390/s130405008 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Dymerski, Tomasz Gębicki, Jacek Wiśniewska, Paulina Śliwińska, Magdalena Wardencki, Waldemar Namieśnik, Jacek Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title | Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title_full | Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title_fullStr | Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title_full_unstemmed | Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title_short | Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers |
title_sort | application of the electronic nose technique to differentiation between model mixtures with copd markers |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673123/ https://www.ncbi.nlm.nih.gov/pubmed/23591962 http://dx.doi.org/10.3390/s130405008 |
work_keys_str_mv | AT dymerskitomasz applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers AT gebickijacek applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers AT wisniewskapaulina applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers AT sliwinskamagdalena applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers AT wardenckiwaldemar applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers AT namiesnikjacek applicationoftheelectronicnosetechniquetodifferentiationbetweenmodelmixtureswithcopdmarkers |