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The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease

The dendritic spines on pyramidal cells represent the main postsynaptic elements of cortical excitatory synapses and they are fundamental structures in memory, learning and cognition. In the present study, we used intracellular injections of Lucifer yellow in fixed tissue to analyse over 19 500 dend...

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Detalles Bibliográficos
Autores principales: Merino-Serrais, Paula, Benavides-Piccione, Ruth, Blazquez-Llorca, Lidia, Kastanauskaite, Asta, Rábano, Alberto, Avila, Jesús, DeFelipe, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673457/
https://www.ncbi.nlm.nih.gov/pubmed/23715095
http://dx.doi.org/10.1093/brain/awt088