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Direct imaging of single UvrD helicase dynamics on long single-stranded DNA
Fluorescence imaging of single-protein dynamics on DNA has been largely limited to double-stranded DNA or short single-stranded DNA. We have developed a hybrid approach for observing single proteins moving on laterally stretched kilobase-sized ssDNA. Here we probed the single-stranded DNA translocas...
Autores principales: | Lee, Kyung Suk, Balci, Hamza, Jia, Haifeng, Lohman, Timothy M., Ha, Taekjip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674262/ https://www.ncbi.nlm.nih.gov/pubmed/23695672 http://dx.doi.org/10.1038/ncomms2882 |
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