TGF-β1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133(+) A549 cell fraction

Metastasis is the leading cause of death by cancer. Non-small-cell lung cancer (NSCLC) represents nearly 85% of primary malignant lung tumours. Recent researches have demonstrated that epithelial-to-mesenchymal transition (EMT) plays a key role in the early process of metastasis of cancer cells. Tra...

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Detalles Bibliográficos
Autores principales: Tirino, V, Camerlingo, R, Bifulco, K, Irollo, E, Montella, R, Paino, F, Sessa, G, Carriero, M V, Normanno, N, Rocco, G, Pirozzi, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674353/
https://www.ncbi.nlm.nih.gov/pubmed/23640462
http://dx.doi.org/10.1038/cddis.2013.144

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