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Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts

Although the recruitment of fibroblasts to areas of injury is critical for wound healing, their subsequent apoptosis is necessary in order to prevent excessive scarring. Fibroproliferative diseases, such as pulmonary fibrosis, are often characterized by fibroblast resistance to apoptosis, but the me...

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Detalles Bibliográficos
Autores principales: Huang, S K, Scruggs, A M, Donaghy, J, Horowitz, J C, Zaslona, Z, Przybranowski, S, White, E S, Peters-Golden, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674355/
https://www.ncbi.nlm.nih.gov/pubmed/23640463
http://dx.doi.org/10.1038/cddis.2013.146

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