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Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells

Small cell lung cancer (SCLC) accounts for nearly 15% of human lung cancers and is one of the most aggressive solid tumors. The SCLC cells are thought to derive from self-renewing pulmonary neuroendocrine cells by oncogenic transformation. However, whether the SCLC cells possess stemness and plastic...

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Detalles Bibliográficos
Autores principales: Zhang, Z, Zhou, Y, Qian, H, Shao, G, Lu, X, Chen, Q, Sun, X, Chen, D, Yin, R, Zhu, H, Shao, Q, Xu, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674360/
https://www.ncbi.nlm.nih.gov/pubmed/23681228
http://dx.doi.org/10.1038/cddis.2013.152