Loss of connective tissue growth factor as an unfavorable prognosis factor activates miR-18b by PI3K/AKT/C-Jun and C-Myc and promotes cell growth in nasopharyngeal carcinoma

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Connective tissue growth factor (CTGF) has different roles in different types of cancer. However, the involvement and molecular basis of CTGF in tumor progression and prognosis of human nasopharyngeal carcinoma (NPC) have almost never been reported. In this study, we observed that downregulated CTGF...

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Detalles Bibliográficos
Autores principales: Yu, X, Zhen, Y, Yang, H, Wang, H, Zhou, Y, Wang, E, Marincola, F M, Mai, C, Chen, Y, Wei, H, Song, Y, Lyu, X, Ye, Y, Cai, L, Wu, Q, Zhao, M, Hua, S, Fu, Q, Zhang, Y, Yao, K, Liu, Z, Li, X, Fang, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674361/
https://www.ncbi.nlm.nih.gov/pubmed/23681229
http://dx.doi.org/10.1038/cddis.2013.153

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