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Antitumor activity of IL-32β through the activation of lymphocytes, and the inactivation of NF-κB and STAT3 signals

Cytokine and activation of lymphocytes are critical for tumor growth. We investigated whether interleukin (IL)-32β overexpression changes other cytokine levels and activates cytotoxic lymphocyte, and thus modify tumor growth. Herein, IL-32β inhibited B16 melanoma growth in IL-32β-overexpressing tran...

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Detalles Bibliográficos
Autores principales: Yun, H-M, Oh, J H, Shim, J-H, Ban, J O, Park, K-R, Kim, J-H, Lee, D H, Kang, J-W, Park, Y H, Yu, D, Kim, Y, Han, S B, Yoon, D-Y, Hong, J T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674373/
https://www.ncbi.nlm.nih.gov/pubmed/23703385
http://dx.doi.org/10.1038/cddis.2013.166