Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells

DNA-dependent protein kinase (DNA-PK) has an important role in the repair of DNA damage and regulates the radiation sensitivity of glioblastoma cells. The VCP (valosine-containing protein), a chaperone protein that regulates ubiquitin-dependent protein degradation, is phosphorylated by DNA-PK and re...

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Detalles Bibliográficos
Autores principales: Jiang, N, Shen, Y, Fei, X, Sheng, K, Sun, P, Qiu, Y, Larner, J, Cao, L, Kong, X, Mi, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674378/
https://www.ncbi.nlm.nih.gov/pubmed/23722536
http://dx.doi.org/10.1038/cddis.2013.171

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