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Caspase-1 is a novel target of p63 in tumor suppression

p63 is a p53 family transcription factor, which besides unique roles in epithelial development, shares tumor suppressive activity with its homolog p53. The p63 gene has different transcriptional start sites, which generate two N-terminal isoforms (transactivation domain (TA)p63 and amino terminal tr...

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Detalles Bibliográficos
Autores principales: Celardo, I, Grespi, F, Antonov, A, Bernassola, F, Garabadgiu, A V, Melino, G, Amelio, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674380/
https://www.ncbi.nlm.nih.gov/pubmed/23703390
http://dx.doi.org/10.1038/cddis.2013.175