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Caspase-1 is a novel target of p63 in tumor suppression
p63 is a p53 family transcription factor, which besides unique roles in epithelial development, shares tumor suppressive activity with its homolog p53. The p63 gene has different transcriptional start sites, which generate two N-terminal isoforms (transactivation domain (TA)p63 and amino terminal tr...
Autores principales: | Celardo, I, Grespi, F, Antonov, A, Bernassola, F, Garabadgiu, A V, Melino, G, Amelio, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674380/ https://www.ncbi.nlm.nih.gov/pubmed/23703390 http://dx.doi.org/10.1038/cddis.2013.175 |
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