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Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs
AIM: Cancer stem cells have the capacity to initiate and sustain tumor growth. In this study, we established a CD44(+) colorectal cancer stem cell line with particular emphasis on its self-renewal capacity, enhanced tumor initiation and drug resistance. METHODS: Fresh colon cancer and paired normal...
Autores principales: | Rao, Guan-hua, Liu, Hong-min, Li, Bao-wei, Hao, Jia-jie, Yang, Yan-lei, Wang, Ming-rong, Wang, Xiao-hui, Wang, Jun, Jin, Hai-jing, Du, Lei, Chen, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674520/ https://www.ncbi.nlm.nih.gov/pubmed/23736004 http://dx.doi.org/10.1038/aps.2013.56 |
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