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The extracellular space and epileptic activity in the adult brain: Explaining the antiepileptic effects of furosemide and bumetanide

Treatments that modulate the size of the extracellular space (ECS) also block epileptiform activity in adult brain tissue. This includes the loop diuretics furosemide and bumetanide, and alterations of the osmolarity of the ECS. These treatments block epileptiform activity in a variety of laboratory...

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Detalles Bibliográficos
Autor principal: Hochman, Daryl W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674522/
https://www.ncbi.nlm.nih.gov/pubmed/22612805
http://dx.doi.org/10.1111/j.1528-1167.2012.03471.x