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A Simple and Fast Two-Locus Quality Control Test to Detect False Positives Due to Batch Effects in Genome-Wide Association Studies
The impact of erroneous genotypes having passed standard quality control (QC) can be severe in genome-wide association studies, genotype imputation, and estimation of heritability and prediction of genetic risk based on single nucleotide polymorphisms (SNP). To detect such genotyping errors, a simpl...
Autores principales: | Lee, Sang Hong, Nyholt, Dale R, Macgregor, Stuart, Henders, Anjali K, Zondervan, Krina T, Montgomery, Grant W, Visscher, Peter M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674525/ https://www.ncbi.nlm.nih.gov/pubmed/21104888 http://dx.doi.org/10.1002/gepi.20541 |
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