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Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice

INTRODUCTION: To investigate the role of interferon-gamma (IFN-γ) in the onset and severity of dacryoadenitis in the CD25 knockout (KO) mouse model of Sjögren Syndrome. METHODS: CD25/IFN-γ double KO (γDKO) mice were created by crossbreeding CD25KO and IFN-γKO mice. Mice were used at 8, 12, and 16 we...

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Detalles Bibliográficos
Autores principales:	Pelegrino, Flavia SA, Volpe, Eugene A, Gandhi, Niral B, Li, De-Quan, Pflugfelder, Stephen C, de Paiva, Cintia S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674599/ https://www.ncbi.nlm.nih.gov/pubmed/23116218 http://dx.doi.org/10.1186/ar4077

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