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Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis
INTRODUCTION: The goal of this study is to investigate whether the -308G > A promoter polymorphism in the tumor necrosis factor alpha (TNFA) gene is associated with disease severity and radiologic joint damage in a large cohort of patients with rheumatoid arthritis (RA). METHODS: A long-term obse...
Autores principales: | Toonen, Erik JM, Barrera, Pilar, Fransen, Jaap, de Brouwer, Arjan PM, Eijsbouts, Agnes M, Miossec, Pierre, Marotte, Hubert, Scheffer, Hans, van Riel, Piet LCM, Franke, Barbara, Coenen, Marieke JH |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674610/ https://www.ncbi.nlm.nih.gov/pubmed/23217265 http://dx.doi.org/10.1186/ar4110 |
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