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Emergence in Elderly Patient Undergoing General Anesthesia with Xenon

Introduction. It is a consensus that the postoperative cognitive function is impaired in elderly patients after general anaesthesia, and such category patient takes more time to recover. Xenon is a noble gas with anesthetic properties mediated by antagonism of N-methyl-D-aspartate receptors. With a...

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Autores principales: Sanfilippo, Maria, Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad, Paparazzo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674643/
https://www.ncbi.nlm.nih.gov/pubmed/23762640
http://dx.doi.org/10.1155/2013/736790
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author Sanfilippo, Maria
Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Paparazzo, Antonella
author_facet Sanfilippo, Maria
Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Paparazzo, Antonella
author_sort Sanfilippo, Maria
collection PubMed
description Introduction. It is a consensus that the postoperative cognitive function is impaired in elderly patients after general anaesthesia, and such category patient takes more time to recover. Xenon is a noble gas with anesthetic properties mediated by antagonism of N-methyl-D-aspartate receptors. With a minimum alveolar concentration of 0.63, xenon is intended for maintaining hypnosis with 30% oxygen. The fast recovery after xenon anaesthesia was hypothesized to be advantageous in this scenario. Case Presentation. We report the case of 99-year-old woman who underwent sigmoid colon carcinoma resection with colorectal anastomosis. We carried out the induction phase by propofol, oxygen, fentanil, and rocuronium bromide, and then we proceeded to a rapid sequence endotracheal intubation consequently. The patient was monitored by IBP, NIBP, ECG, cardiac frequency, respiratory rate, capnometry, TOF Guard, blood gas analysis, and BIS. For maintenance we administrated oxygen, remifentanil, rocuronium bromide, and xenon gas 60–65%. Shortly after the end of surgery the patients started an autonomous respiratory activity, and a high BIS level was also recorded. Decision was made by our team to proceed into the emergence phase. The residual neuromuscular block was antagonized by sugammadex, modified Aldrete score was implicated, and we got our patient fully awake without any cognitive dysfunction or delirium. Conclusion. The rapid emergence to full orientation in very elderly patient who had been anesthetized by xenon shows concordance to the high BIS values and the clinical signs of the depth of anesthesia.
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spelling pubmed-36746432013-06-12 Emergence in Elderly Patient Undergoing General Anesthesia with Xenon Sanfilippo, Maria Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad Paparazzo, Antonella Case Rep Anesthesiol Case Report Introduction. It is a consensus that the postoperative cognitive function is impaired in elderly patients after general anaesthesia, and such category patient takes more time to recover. Xenon is a noble gas with anesthetic properties mediated by antagonism of N-methyl-D-aspartate receptors. With a minimum alveolar concentration of 0.63, xenon is intended for maintaining hypnosis with 30% oxygen. The fast recovery after xenon anaesthesia was hypothesized to be advantageous in this scenario. Case Presentation. We report the case of 99-year-old woman who underwent sigmoid colon carcinoma resection with colorectal anastomosis. We carried out the induction phase by propofol, oxygen, fentanil, and rocuronium bromide, and then we proceeded to a rapid sequence endotracheal intubation consequently. The patient was monitored by IBP, NIBP, ECG, cardiac frequency, respiratory rate, capnometry, TOF Guard, blood gas analysis, and BIS. For maintenance we administrated oxygen, remifentanil, rocuronium bromide, and xenon gas 60–65%. Shortly after the end of surgery the patients started an autonomous respiratory activity, and a high BIS level was also recorded. Decision was made by our team to proceed into the emergence phase. The residual neuromuscular block was antagonized by sugammadex, modified Aldrete score was implicated, and we got our patient fully awake without any cognitive dysfunction or delirium. Conclusion. The rapid emergence to full orientation in very elderly patient who had been anesthetized by xenon shows concordance to the high BIS values and the clinical signs of the depth of anesthesia. Hindawi Publishing Corporation 2013 2013-05-22 /pmc/articles/PMC3674643/ /pubmed/23762640 http://dx.doi.org/10.1155/2013/736790 Text en Copyright © 2013 Maria Sanfilippo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sanfilippo, Maria
Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Paparazzo, Antonella
Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title_full Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title_fullStr Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title_full_unstemmed Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title_short Emergence in Elderly Patient Undergoing General Anesthesia with Xenon
title_sort emergence in elderly patient undergoing general anesthesia with xenon
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674643/
https://www.ncbi.nlm.nih.gov/pubmed/23762640
http://dx.doi.org/10.1155/2013/736790
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