Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins

Endoplasmic reticulum (ER) stress in intestinal secretory cells has been linked with colitis in mice and inflammatory bowel disease (IBD). Endogenous intestinal glucocorticoids are important for homeostasis and glucocorticoid drugs are efficacious in IBD. In Winnie mice with intestinal ER stress cau...

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Detalles Bibliográficos
Autores principales: Das, Indrajit, Png, Chin Wen, Oancea, Iulia, Hasnain, Sumaira Z., Lourie, Rohan, Proctor, Martina, Eri, Rajaraman D., Sheng, Yong, Crane, Denis I., Florin, Timothy H., McGuckin, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674691/
https://www.ncbi.nlm.nih.gov/pubmed/23650437
http://dx.doi.org/10.1084/jem.20121268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674691/
https://www.ncbi.nlm.nih.gov/pubmed/23650437
http://dx.doi.org/10.1084/jem.20121268

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