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IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells
The emergence of the adaptive immune system took a toll in the form of pathologies mediated by self-reactive cells. Regulatory T cells (T reg cells) exert a critical brake on responses of T and B lymphocytes to self- and foreign antigens. Here, we asked whether T reg cells are required to restrain N...
Autores principales: | Gasteiger, Georg, Hemmers, Saskia, Firth, Matthew A., Le Floc’h, Audrey, Huse, Morgan, Sun, Joseph C., Rudensky, Alexander Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674692/ https://www.ncbi.nlm.nih.gov/pubmed/23650441 http://dx.doi.org/10.1084/jem.20122462 |
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