Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation

Retinoic acid (RA), a vitamin A metabolite, modulates mucosal T helper cell responses. Here we examined the role of RA in regulating IL-22 production by γδ T cells and innate lymphoid cells in intestinal inflammation. RA significantly enhanced IL-22 production by γδ T cells stimulated in vitro with...

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Detalles Bibliográficos
Autores principales: Mielke, Lisa A., Jones, Sarah A., Raverdeau, Mathilde, Higgs, Rowan, Stefanska, Anna, Groom, Joanna R., Misiak, Alicja, Dungan, Lara S., Sutton, Caroline E., Streubel, Gundula, Bracken, Adrian P., Mills, Kingston H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674702/
https://www.ncbi.nlm.nih.gov/pubmed/23690441
http://dx.doi.org/10.1084/jem.20121588

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