Cargando…

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

Fibroblast activation protein (FAP) is a candidate universal target antigen because it has been reported to be selectively expressed in nearly all solid tumors by a subset of immunosuppressive tumor stromal fibroblasts. We verified that 18/18 human tumors of various histologies contained pronounced...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Eric, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Morgan, Richard A., Lee, Chyi-Chia Richard, Restifo, Nicholas P., Rosenberg, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674706/
https://www.ncbi.nlm.nih.gov/pubmed/23712432
http://dx.doi.org/10.1084/jem.20130110

Ejemplares similares