Paraoxonase-1 Inhibits Oxidized Low-Density Lipoprotein-Induced Metabolic Alterations and Apoptosis in Endothelial Cells: A Nondirected Metabolomic Study

We studied the influence of PON1 on metabolic alterations induced by oxidized LDL when incubated with endothelial cells. HUVEC cells were incubated with native LDL, oxidized LDL, oxidized LDL plus HDL from wild type mice, and oxidized LDL plus HDL from PON1-deficient mice. Results showed alterations...

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Detalles Bibliográficos
Autores principales: García-Heredia, Anabel, Marsillach, Judit, Rull, Anna, Triguero, Iris, Fort, Isabel, Mackness, Bharti, Mackness, Michael, Shih, Diana M., Joven, Jorge, Camps, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674710/
https://www.ncbi.nlm.nih.gov/pubmed/23766557
http://dx.doi.org/10.1155/2013/156053

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