Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing

Abnormal metabolism of the tau protein is central to the pathogenesis of a number of dementias, including Alzheimer's disease. Aberrant alternative splicing of exon 10 in the tau pre-mRNA resulting in an imbalance of tau isoforms is one of the molecular causes of the inherited tauopathy, FTDP-1...

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Detalles Bibliográficos
Autores principales: Avale, María Elena, Rodríguez-Martín, Teresa, Gallo, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674800/
https://www.ncbi.nlm.nih.gov/pubmed/23459933
http://dx.doi.org/10.1093/hmg/ddt108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674800/
https://www.ncbi.nlm.nih.gov/pubmed/23459933
http://dx.doi.org/10.1093/hmg/ddt108

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