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Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis

The Vesicle-associated membrane protein (VAMP)-Associated Protein B (VAPB) is the causative gene of amyotrophic lateral sclerosis 8 (ALS8) in humans. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by selective death of motor neurons leading to spasticity...

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Detalles Bibliográficos
Autores principales:	Forrest, Stuart, Chai, Andrea, Sanhueza, Mario, Marescotti, Manuela, Parry, Katherine, Georgiev, Atanas, Sahota, Virender, Mendez-Castro, Raquel, Pennetta, Giuseppa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674808/ https://www.ncbi.nlm.nih.gov/pubmed/23492670 http://dx.doi.org/10.1093/hmg/ddt118

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