Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in cervical cancer

BACKGROUND: Multiple studies proved that miRNAs have a causal role in tumorigenesis. Some miRNAs are regulated by epigenetic alterations in their promoter regions and can be activated by chromatin- modifying drugs. METHODS: We treated cervical cancer cells with 5-aza-2’-deoxycytidine and get a micro...

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Detalles Bibliográficos
Autores principales: Yao, Tingting, Rao, Qunxian, Liu, Longyang, Zheng, Chengyu, Xie, Qingsheng, Liang, Jinxiao, Lin, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674919/
https://www.ncbi.nlm.nih.gov/pubmed/23732000
http://dx.doi.org/10.1186/1743-422X-10-175

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