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Single-molecule photobleaching reveals increased MET receptor dimerization upon ligand binding in intact cells

BACKGROUND: The human receptor tyrosine kinase MET and its ligand hepatocyte growth factor/scatter factor are essential during embryonic development and play an important role during cancer metastasis and tissue regeneration. In addition, it was found that MET is also relevant for infectious disease...

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Detalles Bibliográficos
Autores principales:	Dietz, Marina S, Haße, Daniel, Ferraris, Davide M, Göhler, Antonia, Niemann, Hartmut H, Heilemann, Mike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674922/ https://www.ncbi.nlm.nih.gov/pubmed/23731667 http://dx.doi.org/10.1186/2046-1682-6-6

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