ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response

BACKGROUND: The Grin1 (glutamate receptor, ionotropic, NMDA1) gene expresses a subunit of N-methyl-D-aspartate (NMDA) receptors that is considered to play an important role in excitatory neurotransmission, synaptic plasticity, and brain development. Grin1 is a candidate susceptibility gene for neuro...

Descripción completa

Detalles Bibliográficos
Autores principales: Umemori, Juzoh, Takao, Keizo, Koshimizu, Hisatsugu, Hattori, Satoko, Furuse, Tamio, Wakana, Shigeharu, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674941/
https://www.ncbi.nlm.nih.gov/pubmed/23688147
http://dx.doi.org/10.1186/1756-0500-6-203

Ejemplares similares

Ejemplares similares