Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis

There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT. The development of oral medications is a key objective of the Consor...

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Detalles Bibliográficos
Autores principales: Thuita, John K., Wolf, Kristina K., Murilla, Grace A., Liu, Qiang, Mutuku, James N., Chen, Yao, Bridges, Arlene S., Mdachi, Raymond E., Ismail, Mohamed A., Ching, Shelley, Boykin, David W., Hall, James Edwin, Tidwell, Richard R., Paine, Mary F., Brun, Reto, Wang, Michael Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674995/
https://www.ncbi.nlm.nih.gov/pubmed/23755309
http://dx.doi.org/10.1371/journal.pntd.0002230

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