Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle

Mammalian DNA replication starts at distinct chromosomal sites in a tissue-specific pattern coordinated with transcription, but previous studies have not yet identified a chromatin modification that correlates with the initiation of DNA replication at particular genomic locations. Here we report tha...

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Detalles Bibliográficos
Autores principales: Fu, Haiqing, Maunakea, Alika K., Martin, Melvenia M., Huang, Liang, Zhang, Ya, Ryan, Michael, Kim, RyangGuk, Lin, Chii Meil, Zhao, Keji, Aladjem, Mirit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674996/
https://www.ncbi.nlm.nih.gov/pubmed/23754963
http://dx.doi.org/10.1371/journal.pgen.1003542

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