Cargando…

Enhancing Pancreatic Beta-Cell Regeneration In Vivo with Pioglitazone and Alogliptin

AIMS/HYPOTHESIS: Pancreatic beta-cells retain limited ability to regenerate and proliferate after various physiologic triggers. Identifying therapies that are able to enhance beta-cell regeneration may therefore be useful for the treatment of both type 1 and type 2 diabetes. METHODS: In this study w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Hao, Park, Soo-Young, Wang, Xiao-Jun, Misawa, Ryosuke, Grossman, Eric J., Tao, Jing, Zhong, Rong, Witkowski, Piotr, Bell, Graeme I., Chong, Anita S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675063/ https://www.ncbi.nlm.nih.gov/pubmed/23762423 http://dx.doi.org/10.1371/journal.pone.0065777

Ejemplares similares

Alogliptin in combination with metformin and pioglitazone for the treatment of type 2 diabetes mellitus
por: Holland, Daniel Q, et al.
Publicado: (2014)

Glycemic Control Promotes Pancreatic Beta-Cell Regeneration in Streptozotocin-Induced Diabetic Mice
por: Grossman, Eric J., et al.
Publicado: (2010)

Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment
por: Triplitt, Curtis, et al.
Publicado: (2010)

Initial Combination Therapy With Alogliptin and Pioglitazone in Drug-Naïve Patients With Type 2 Diabetes
por: Rosenstock, Julio, et al.
Publicado: (2010)

Comparison of Efficacy of Glimepiride, Alogliptin, and Alogliptin-Pioglitazone as the Initial Periods of Therapy in Patients with Poorly Controlled Type 2 Diabetes Mellitus: An Open-Label, Multicenter, Randomized, Controlled Study
por: Kim, Hae Jin, et al.
Publicado: (2022)

Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study
por: Kim, Jeong Mi, et al.
Publicado: (2020)

Necrotizing Pancreatitis Secondary to Hydrochlorothiazide and Alogliptin: A Case Report
por: Del Rio, Teresa, et al.
Publicado: (2023)

Fixed-dose combination of alogliptin/pioglitazone improves glycemic control in Japanese patients with type 2 diabetes mellitus independent of body mass index
por: Aoki, Chie, et al.
Publicado: (2017)

Neuroprotective effect of alogliptin on oxaliplatin-induced peripheral neuropathy in vivo and in vitro
por: Shigematsu, Nao, et al.
Publicado: (2020)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

Dipeptidyl-Peptidase-IV Inhibitors, Imigliptin and Alogliptin, Improve Beta-Cell Function in Type 2 Diabetes
por: Liu, Xu, et al.
Publicado: (2021)

Alogliptin benzoate for management of type 2 diabetes
por: Saisho, Yoshifumi
Publicado: (2015)

Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice
por: Bailey, Kathleen A., et al.
Publicado: (2015)

Efficacy and safety of alogliptin in a pediatric patient with maturity-onset diabetes of the young type 1
por: Tonouchi, Ryosuke, et al.
Publicado: (2017)

Quantitative Analysis of Pancreatic Polypeptide Cell Distribution in the Human Pancreas
por: Wang, Xiaojun, et al.
Publicado: (2013)

Alogliptin: a new addition to the class of DPP-4 inhibitors
por: Andukuri, Radha, et al.
Publicado: (2009)

Liquid Chromatographic Determination of Alogliptin in Bulk and in its Pharmaceutical Preparation
por: El-Bagary, Ramzia I., et al.
Publicado: (2012)

Alogliptin-Induced Minimal Change Nephrotic Syndrome and Interstitial Nephritis
por: Shima, Hisato, et al.
Publicado: (2019)

Oxidative Stress in Pancreatic Beta Cell Regeneration
por: Wang, Jingjing, et al.
Publicado: (2017)

Potent antiatherosclerotic effects of alogliptin in addition to its potent antidiabetic effects
por: Kapoor, Shailendra
Publicado: (2012)

Alogliptin improves survival and health of mice on a high‐fat diet
por: Zhu, Biao, et al.
Publicado: (2019)

Effects of metformin and alogliptin on body composition in people with type 2 diabetes
por: Takeshita, Yumie, et al.
Publicado: (2018)

Efficacy and Safety of Alogliptin in Elderly Patients With Type 2 Diabetes Mellitus
por: Takeda, Hiroshi, et al.
Publicado: (2019)

Immunohistochemical Pharmacokinetics of the Anti-diabetes Drug Alogliptin in Rat Kidney and Liver
por: Yamamoto, Yutaro, et al.
Publicado: (2020)

Benefit-Risk Assessment of Alogliptin for the Treatment of Type 2 Diabetes Mellitus
por: Kaku, Kohei, et al.
Publicado: (2019)

Pioglitazone inhibits the proliferation and metastasis of human pancreatic cancer cells
por: NINOMIYA, ITASU, et al.
Publicado: (2014)

Treatment of Streptozotocin-Induced Diabetic Rats with Alogliptin: Effect on Vascular and Neural Complications
por: Davidson, Eric P., et al.
Publicado: (2011)

Dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapy – focus on alogliptin
por: Capuano, Annalisa, et al.
Publicado: (2013)

Ethnic Differences in Efficacy and Safety of Alogliptin: A Systematic Review and Meta-Analysis
por: Cai, Yuli, et al.
Publicado: (2017)

The pharmacokinetics and pharmacodynamics of alogliptin in children, adolescents, and adults with type 2 diabetes mellitus
por: Dudkowski, Caroline, et al.
Publicado: (2016)

Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation
por: Bramhane, Dinesh M., et al.
Publicado: (2016)

Therapeutic effect and potential mechanism of pioglitazone in rats with severe acute pancreatitis
por: Hai, Wang, et al.
Publicado: (2017)

Efficacy and Safety of Alogliptin in Patients With Type 2 Diabetes: Analysis of the ATTAK-J Study
por: Takeda, Hiroshi, et al.
Publicado: (2016)

Evaluation of the Effect of Alogliptin on Tissue Characteristics of the Carotid Wall: Subanalysis of the SPEAD-A Trial
por: Irie, Yoko, et al.
Publicado: (2018)

Development and Validation of an HPLC Method for Determination of Antidiabetic Drug Alogliptin Benzoate in Bulk and Tablets
por: Naseef, Hani, et al.
Publicado: (2018)

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits
por: Zhang, Xiaowei, et al.
Publicado: (2018)

Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin
por: Jurczyk, Agata, et al.
Publicado: (2013)

Regional Differences in Islet Distribution in the Human Pancreas - Preferential Beta-Cell Loss in the Head Region in Patients with Type 2 Diabetes
por: Wang, Xiaojun, et al.
Publicado: (2013)

MicroRNA Expression in Alpha and Beta Cells of Human Pancreatic Islets
por: Klein, Dagmar, et al.
Publicado: (2013)

Pioglitazone: Indian perspective
por: Shukla, Rishi, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_16m7apt037892tug9rb4jb83dp