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Electrophysiologic Biomarkers for Assessing Disease Progression and the Effect of Riluzole in SOD1 G93A ALS Mice

OBJECTIVE: To compare electrical impedance myography (EIM) 50 kHz phase to weight, motor score, paw grip endurance (PGE), CMAP amplitude, and MUNE for the identification of disease progression and the effect of riluzole in the SOD1 G93A mouse. METHODS: Twenty-three animals received 8 mg/kg/day riluz...

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Detalles Bibliográficos
Autores principales:	Li, Jia, Sung, Minhee, Rutkove, Seward B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675066/ https://www.ncbi.nlm.nih.gov/pubmed/23762454 http://dx.doi.org/10.1371/journal.pone.0065976

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