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Interaction between NBS1 and the mTOR/Rictor/SIN1 Complex through Specific Domains

Nijmegen breakage syndrome (NBS) is a chromosomal-instability syndrome. The NBS gene product, NBS1 (p95 or nibrin), is a part of the Mre11-Rad50-NBS1 complex. SIN1 is a component of the mTOR/Rictor/SIN1 complex mediating the activation of Akt. Here we show that NBS1 interacted with mTOR, Rictor, and...

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Detalles Bibliográficos
Autores principales:	Wang, Jian-Qiu, Chen, Jian-Hong, Chen, Yen-Chung, Chen, Mei-Yu, Hsieh, Chia-Ying, Teng, Shu-Chun, Wu, Kou-Juey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675082/ https://www.ncbi.nlm.nih.gov/pubmed/23762398 http://dx.doi.org/10.1371/journal.pone.0065586

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