Promoter DNA Methylation Pattern Identifies Prognostic Subgroups in Childhood T-Cell Acute Lymphoblastic Leukemia

BACKGROUND: Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but there is a considerable fraction of patients experiencing a poor outcome. There is a need for better prognostic markers and aberrant DNA methylation is a candidate in other malignancies, but its potentia...

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Detalles Bibliográficos
Autores principales: Borssén, Magnus, Palmqvist, Lars, Karrman, Kristina, Abrahamsson, Jonas, Behrendtz, Mikael, Heldrup, Jesper, Forestier, Erik, Roos, Göran, Degerman, Sofie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675104/
https://www.ncbi.nlm.nih.gov/pubmed/23762353
http://dx.doi.org/10.1371/journal.pone.0065373

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