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Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging

The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb’s single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate-dependent dioxygenase that catalyzes the oxidation and...

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Detalles Bibliográficos
Autores principales: Sogi, Kimberly M., Gartner, Zev J., Breidenbach, Mark A., Appel, Mason J., Schelle, Michael W., Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675115/
https://www.ncbi.nlm.nih.gov/pubmed/23762287
http://dx.doi.org/10.1371/journal.pone.0065080