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The Role of the E3 Ligase Cbl-B in Murine Dendritic Cells

Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...

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Detalles Bibliográficos
Autores principales: Wallner, Stephanie, Lutz-Nicoladoni, Christina, Tripp, Christoph H., Gastl, Günther, Baier, Gottfried, Penninger, Josef M., Stoitzner, Patrizia, Wolf, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675148/
https://www.ncbi.nlm.nih.gov/pubmed/23762309
http://dx.doi.org/10.1371/journal.pone.0065178