Cargando…

The Role of the E3 Ligase Cbl-B in Murine Dendritic Cells

Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wallner, Stephanie, Lutz-Nicoladoni, Christina, Tripp, Christoph H., Gastl, Günther, Baier, Gottfried, Penninger, Josef M., Stoitzner, Patrizia, Wolf, Dominik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675148/ https://www.ncbi.nlm.nih.gov/pubmed/23762309 http://dx.doi.org/10.1371/journal.pone.0065178

Ejemplares similares

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b
por: Lutz-Nicoladoni, Christina, et al.
Publicado: (2015)

Releasing the Brake: Targeting Cbl-b to Enhance Lymphocyte Effector Functions
por: Wallner, Stephanie, et al.
Publicado: (2012)

Adoptive Transfer of siRNA Cblb-Silenced CD8(+) T Lymphocytes Augments Tumor Vaccine Efficacy in a B16 Melanoma Model
por: Hinterleitner, Reinhard, et al.
Publicado: (2012)

Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells
por: Tong, Haijun, et al.
Publicado: (2021)

Regulation of Lymphatic GM-CSF Expression by the E3 Ubiquitin Ligase Cbl-b
por: Peer, Sebastian, et al.
Publicado: (2018)

Murine Langerin(+) dermal dendritic cells prime CD8(+) T cells while Langerhans cells induce cross-tolerance
por: Flacher, Vincent, et al.
Publicado: (2014)

Murine Langerin(+) dermal dendritic cells prime CD8(+) T cells while Langerhans cells induce cross-tolerance
por: Flacher, Vincent, et al.
Publicado: (2014)

Cytip regulates dendritic-cell function in contact hypersensitivity
por: Heib, Valeska, et al.
Publicado: (2012)

PKCα and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription
por: Christina, Lutz-Nicoladoni, et al.
Publicado: (2013)

Corrigendum to “PKC∝ and PKCβ cooperate functionally in CD3-induced de novo IL-2 mRNA transcription” [Immunol. Lett. 151 (1–2) (2013) 31–38)]
por: Lutz-Nicoladoni, Christina, et al.
Publicado: (2014)

E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation
por: Qiao, Guilin, et al.
Publicado: (2014)

Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping
por: Hornsteiner, Florian, et al.
Publicado: (2022)

Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature
por: Singh, Tej Pratap, et al.
Publicado: (2018)

Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy
por: An, Wei, et al.
Publicado: (2015)

E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
por: Ahmed, Syed Feroj, et al.
Publicado: (2021)

Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
por: Matalon, Omri, et al.
Publicado: (2016)

Differential infection of murine and human dendritic cell subsets by oncolytic vesicular stomatitis virus variants
por: Pipperger, Lisa, et al.
Publicado: (2021)

Human skin dendritic cells can be targeted in situ by intradermal injection of antibodies against lectin receptors
por: Stoitzner, Patrizia, et al.
Publicado: (2014)

Murine Melanoma-Infiltrating Dendritic Cells Are Defective in Antigen Presenting Function Regardless of the Presence of CD4(+)CD25(+) Regulatory T Cells
por: Ataera, Haley, et al.
Publicado: (2011)

LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling
por: Scheffler, Julia M., et al.
Publicado: (2014)

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses
por: Clausen, Björn E., et al.
Publicado: (2015)

Spontaneous tumor rejection by cbl-b–deficient CD8(+) T cells
por: Loeser, Stefanie, et al.
Publicado: (2007)

PKCθ/β and CYLD Are Antagonistic Partners in the NFκB and NFAT Transactivation Pathways in Primary Mouse CD3(+) T Lymphocytes
por: Thuille, Nikolaus, et al.
Publicado: (2013)

Guidelines for diagnosis and management of the cobalamin-related remethylation disorders cblC, cblD, cblE, cblF, cblG, cblJ and MTHFR deficiency
por: Huemer, Martina, et al.
Publicado: (2016)

The E3 Ubiquitin Ligase Cbl-b Predicts Favorable Prognosis in Breast Cancer
por: Liu, Xiuming, et al.
Publicado: (2020)

Fluctuations in AKT and PTEN Activity Are Linked by the E3 Ubiquitin Ligase cCBL
por: Olazábal-Morán, Manuel, et al.
Publicado: (2021)

Antigen targeting to dendritic cells: Still a place in future immunotherapy?
por: Stoitzner, Patrizia, et al.
Publicado: (2022)

Combining chemotherapy and autologous peptide‐pulsed dendritic cells provides survival benefit in stage IV melanoma patients
por: Eisendle, Klaus, et al.
Publicado: (2020)

Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b
por: Kwon, Ji Hye, et al.
Publicado: (2019)

The Role of E3 Ubiquitin Ligase Cbl Proteins in Interleukin-2-Induced Jurkat T-Cell Activation
por: Zhao, Ming-Fang, et al.
Publicado: (2013)

SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function
por: Anderson, Courtney, et al.
Publicado: (2012)

IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases
por: Schmid, Fabian Marc, et al.
Publicado: (2018)

Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1
por: Zhang, Hong-Guang, et al.
Publicado: (2020)

Negative regulation of receptor tyrosine kinases by ubiquitination: Key roles of the Cbl family of E3 ubiquitin ligases
por: Tang, Rong, et al.
Publicado: (2022)

Ablation of Cbl-b and c-Cbl in dendritic cells causes spontaneous liver cirrhosis via altering multiple properties of CD103(+) cDC1s
por: Xu, Fei, et al.
Publicado: (2022)

Soy Glycinin Contains a Functional Inhibitory Sequence against Muscle-Atrophy-Associated Ubiquitin Ligase Cbl-b
por: Abe, Tomoki, et al.
Publicado: (2013)

Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation
por: Li, Xiaoxiao, et al.
Publicado: (2015)

c-Cbl Acts as an E3 Ligase Against DDA3 for Spindle Dynamics and Centriole Duplication during Mitosis
por: Gwon, Dasom, et al.
Publicado: (2019)

Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells
por: Spinner, Camille A., et al.
Publicado: (2015)

A novel CBL-B(flox/flox) mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells
por: Goetz, Benjamin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bikd5ulsq9rkldp2mucu2ks575