Cargando…
Streptolysin O and its Co-Toxin NAD-glycohydrolase Protect Group A Streptococcus from Xenophagic Killing
Group A Streptococcus (Streptococcus pyogenes or GAS) causes pharyngitis, severe invasive infections, and the post-infectious syndromes of glomerulonephritis and rheumatic fever. GAS can be internalized and killed by epithelial cells in vitro, a process that may contribute to local innate defense ag...
Autores principales: | O'Seaghdha, Maghnus, Wessels, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675196/ https://www.ncbi.nlm.nih.gov/pubmed/23762025 http://dx.doi.org/10.1371/journal.ppat.1003394 |
Ejemplares similares
-
Binding of NAD(+)-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus
por: Velarde, Jorge J., et al.
Publicado: (2017) -
NAD(+)-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus
por: Sharma, Onkar, et al.
Publicado: (2016) -
Streptolysin O and NAD-Glycohydrolase Prevent Phagolysosome Acidification and Promote Group A Streptococcus Survival in Macrophages
por: Bastiat-Sempe, Benedicte, et al.
Publicado: (2014) -
2590. Streptolysin O Enhances Binding of the Group A Streptococcal NAD+-Glycohydrolase Toxin to Oropharyngeal Keratinocytes
por: Velarde, Jorge J, et al.
Publicado: (2019) -
Streptococcus pyogenes NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O
por: McIndoo, Eric R., et al.
Publicado: (2022)