Cargando…
Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family Molecules
Activation of phosphoinositide 3-kinase (PI3K) and Akt (protein kinase B) is a common response triggered by a range of membrane-bound receptors on many cell types. In T lymphocytes, the PI3K-Akt pathway promotes clonal expansion, differentiation, and survival of effector cells and suppresses the gen...
Autores principales: | So, Takanori, Croft, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675380/ https://www.ncbi.nlm.nih.gov/pubmed/23760533 http://dx.doi.org/10.3389/fimmu.2013.00139 |
Ejemplares similares
-
Regulation of the PKCθ-NF-κB Axis in T Lymphocytes by the Tumor Necrosis Factor Receptor Family Member OX40
por: So, Takanori, et al.
Publicado: (2012) -
Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes
por: Wang, Xinxin, et al.
Publicado: (2015) -
Regulation of Tissue Responses: The TWEAK/Fn14 Pathway and Other TNF/TNFR Superfamily Members That Activate Non-Canonical NFκB Signaling
por: Burkly, Linda C.
Publicado: (2015) -
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
por: Liang, Yuejin, et al.
Publicado: (2022) -
Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling
por: Siegmund, Daniela, et al.
Publicado: (2023)