Mitochondrial DNA replication proceeds via a ‘bootlace’ mechanism involving the incorporation of processed transcripts

The observation that long tracts of RNA are associated with replicating molecules of mitochondrial DNA (mtDNA) suggests that the mitochondrial genome of mammals is copied by an unorthodox mechanism. Here we show that these RNA-containing species are present in living cells and tissue, based on inter...

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Detalles Bibliográficos
Autores principales: Reyes, Aurelio, Kazak, Lawrence, Wood, Stuart R., Yasukawa, Takehiro, Jacobs, Howard T., Holt, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675460/
https://www.ncbi.nlm.nih.gov/pubmed/23595151
http://dx.doi.org/10.1093/nar/gkt196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675460/
https://www.ncbi.nlm.nih.gov/pubmed/23595151
http://dx.doi.org/10.1093/nar/gkt196

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