TherMos: Estimating protein–DNA binding energies from in vivo binding profiles

Accurately characterizing transcription factor (TF)-DNA affinity is a central goal of regulatory genomics. Although thermodynamics provides the most natural language for describing the continuous range of TF-DNA affinity, traditional motif discovery algorithms focus instead on classification paradig...

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Detalles Bibliográficos
Autores principales: Sun, Wenjie, Hu, Xiaoming, Lim, Michael H. K., Ng, Calista K. L., Choo, Siew Hua, Castro, Diogo S., Drechsel, Daniela, Guillemot, François, Kolatkar, Prasanna R., Jauch, Ralf, Prabhakar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675472/
https://www.ncbi.nlm.nih.gov/pubmed/23595148
http://dx.doi.org/10.1093/nar/gkt250

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