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Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells

Double-strand break (DSB) repair pathways are critical for the maintenance of genomic integrity and the prevention of tumorigenesis in mammalian cells. Here, we present the development and validation of a novel assay to measure mutagenic non-homologous end-joining (NHEJ) repair in living cells, whic...

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Detalles Bibliográficos
Autores principales:	Bindra, Ranjit S., Goglia, Alexander G., Jasin, Maria, Powell, Simon N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675474/ https://www.ncbi.nlm.nih.gov/pubmed/23585275 http://dx.doi.org/10.1093/nar/gkt255

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