High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases

Transcription activator-like effector nucleases (TALENs) are a powerful new approach for targeted gene disruption in various animal models, but little is known about their activities in Mus musculus, the widely used mammalian model organism. Here, we report that direct injection of in vitro transcri...

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Detalles Bibliográficos
Autores principales: Qiu, Zhongwei, Liu, Meizhen, Chen, Zhaohua, Shao, Yanjiao, Pan, Hongjie, Wei, Gaigai, Yu, Chao, Zhang, Long, Li, Xia, Wang, Ping, Fan, Heng-Yu, Du, Bing, Liu, Bin, Liu, Mingyao, Li, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675477/
https://www.ncbi.nlm.nih.gov/pubmed/23630316
http://dx.doi.org/10.1093/nar/gkt258

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