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Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage

Differentiation of skeletal muscle cells is accompanied by drastic changes in gene expression programs that depend on activation and repression of genes at defined time points. Here we identify the serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) as a corepressor that inhibit...

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Detalles Bibliográficos
Autores principales: de la Vega, Laureano, Hornung, Juliane, Kremmer, Elisabeth, Milanovic, Maja, Schmitz, M. Lienhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675480/
https://www.ncbi.nlm.nih.gov/pubmed/23620283
http://dx.doi.org/10.1093/nar/gkt262