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Details of ssDNA annealing revealed by an HSV-1 ICP8–ssDNA binary complex
Infected cell protein 8 (ICP8) from herpes simplex virus 1 was first identified as a single-strand (ss) DNA-binding protein. It is essential for, and abundant during, viral replication. Studies in vitro have shown that ICP8 stimulates model replication reactions, catalyzes annealing of complementary...
Autores principales: | Tolun, Gökhan, Makhov, Alexander M., Ludtke, Steven J., Griffith, Jack D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675482/ https://www.ncbi.nlm.nih.gov/pubmed/23605044 http://dx.doi.org/10.1093/nar/gkt266 |
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