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A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA
Transcription and mRNA export are linked processes. However, the molecular mechanisms of this coordination are not clear. Sus1 (hENY2) participates in this coordination as part of two protein complexes: SAGA, a transcriptional co-activator; TREX-2, which functions in mRNA biogenesis and export. Here...
Autores principales: | García-Oliver, Encar, Pascual-García, Pau, García-Molinero, Varinia, Lenstra, Tineke L., Holstege, Frank C. P., Rodríguez-Navarro, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675487/ https://www.ncbi.nlm.nih.gov/pubmed/23599000 http://dx.doi.org/10.1093/nar/gkt272 |
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